Background:
Molecular tests allow the
detection of high-
risk human papillomavirus in cervical samples, playing an important
role in the prevention of
cervical cancer.
Objectives:
We performed a study to determine the
prevalence of
HPV 16,
HPV 18 and other high-
risk human papillomavirus (pool 12
genotypes) in Peruvian
females from diverse
urban areas using the cobas 4800 HPV test.
Methods:
Routine cervical samples collected in our
laboratory were analyzed by cobas 4800 HPV test.
Results:
A total of 2247 samples from
female patients aged 17–79 years were tested. high-
risk human papillomavirus was positive in 775 (34.49%) samples. Of these, 641 (82.71%) were single
infections and 134 (17.29%) were multiple
infections. The positivity rates for
HPV 16,
HPV 18, and other high-
risk human papillomavirus were 10.77%, 2.0%, and 28.08%, respectively. In multiple high-
risk human papillomavirus infections, the concomitance of
HPV 16 and other high-
risk human papillomavirus was more prevalent (13.42%).
Conclusion:
Our study showed high
prevalence of high-
risk human papillomavirus in urban
Peru, mainly among young
women. In both single and multiple
infections other high-
risk human papillomavirus were more prevalent than
HPV 16 and
HPV 18, which might influence
vaccine impact in our country. Furthermore, the cobas 4800 HPV test may be considered a useful tool for HPV molecular
diagnosis. .